Image 1. PICH acts like a lookout, spotting and attaching to tiny DNA threads called ultrafine anaphase bridges (UFBs). When ...

OGM uniquely identified a complex chromosomal rearrangement missed by classical cytogenetics, helping clinical researchers apply targeted ...

A nearly gapless genome sequence of the echidna, an egg-laying mammal with multiple sex chromosomes, helps researchers to ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

The short-beaked echidna (Tachyglossus aculeatus) is one of Australia's most iconic animals. Belonging to a unique group of ...

A structural abnormality can include an alteration to the structure of the chromosome, as the name suggests. However, a numerical abnormality means that an individual is either missing one of the ...

Dr Anup Rawool Facioscapulohumeral muscular dystrophy (FSHD) is a genetic condition that affects muscle function, often ...

Representation of human sex chromosomes, Y (top) and X (bottom), with PAR2 seen at the far tips of the long arm on each chromosome. (Kelkar et al., PLOS ONE, 2009/CC BY 2.5/Wikimedia Commons) Together ...

Subsequently, the transcript was quantified by RQ-PCR and a BCR-ABL/ABL ratio of 94.4% was obtained. At the time of diagnosis, most CML patients have an M-bcr BCR-ABL molecular rearrangement ...