The targeting of telomeres offers promise for new cancer therapies, which can be aimed at disrupting the mechanisms that ...

The new finding is published in Cell in an article titled, “ SMC motor proteins extrude DNA asymmetrically and can switch directions ,” and is key to understanding how these motors shape our genome ...

The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

In many organisms, aging is a clear risk factor for increased rates of chromosome mis-segregation, the main source of aneuploidy. Here, we report that old yeast mother c ...

UTA researchers developed a chromosome-level genome map for bedbugs, revealing insights into their biology, evolution, and insecticide resistance, paving the way for improved pest control strategies.

The coordinated termination of DNA replication is an important step in the life cycle of bacteria with circular chromosomes, but has only been defined at a molecular level in two systems to date.