This important theoretical study examines the possibility of encoding genomic information in a collective of short overlapping strands (e.g., the Virtual Circular Genome (VCG) model). The study ...

An orthogonal alphaviral RNA replication system with chemically inducible ... Experiments and simulations suggest monovalent salts destabilize DNA/RNA because of overcharging.

By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...

R-loops can help to turn on specific genes by forming an RNA:DNA "sandwich" in regulatory regions of a target gene. In the case of the NPAS4 gene, R-loops appear to help to bring the enhancer ...

interactions with MAVS in the presence of RNA. After this, they performed screens to see which of these proteins helped induce interferon and were required to restrict virus replication.

PD-L1 not only responds to the cGAS-STING pathway upon DNA damage, but also regulates cGAS-STING to induce inflammation. This ...

In addition, modulation of the m6A machinery affected the type I interferon response after poly-IC transfection, a mimic of RNA virus replication, but did not affect the cellular antiviral ... and ...

Amid the outbreak of human metapneumovirus (HMPV0 virus) in China, countries worldwide have increased their surveillance.

With so many at-home DNA tests now available to consumers, learning more about your ancestry is easier than ever. Plus, these tests make for thoughtful, unique holiday gifts. All you have to do is ...

This escalating risk of a new RNA virus pandemic highlights the urgent need to implement One Health strategies. However, the centralised virus detection systems currently in use fall short of meeting ...

Shelby Brown (she/her/hers) is an editor for CNET's services team. She covers tips and tricks for apps, operating systems and devices, as well as mobile gaming and Apple Arcade news. Shelby also ...