Optically pure alcohols are prevalent motifs in natural products and pharmaceuticals, driving the development of effective ...

Temperature affects enzyme-catalysed reactions by influencing the rate at which they occur. For a reaction to occur between an enzyme and substrate the two molecules need to collide. At lower ...

As humans do not synthesize dTDP-l-rhamnose, the four enzymes of its metabolic pathway ... phosphate and mannose-6-phosphate via an ene-diol intermediate. Superposition of PMI and RmlC based ...

College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, Zhejiang, China ...

United Kingdom, London, Jan. 03, 2025 (GLOBE NEWSWIRE) -- Introspective Market Research is excited to announce the launch of its latest publication, the "Food Enzymes Market" report. This in-depth ...

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...

Centre for Engineering Biology, Institute of Quantitative Biology, Biochemistry and Biotechnology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FF, U.K. Centre for ...

Nanozymes, like natural enzymes, can effectively catalyze the conversion of enzyme substrates under mild conditions and exhibit similar catalytic efficiency and enzymatic reaction kinetics. Moreover, ...

Methamphetamine behaves as both a weak substrate and competitive inhibitor of CYP2D6, while MDMA acts as a high affinity substrate and potent mechanism-based inhibitor (MBI) of the enzyme. The MBI ...

Diabetes is a leading cause of global mortality and disability, and its economic burden is substantial. This Review focuses on type 2 diabetes, which makes up 90–95% of all diabetes cases. Type 2 ...

However, the reason for their enhanced selectivity has not yet been examined enough, nor has the range of substrates suitable ... a magnesium phosphonoenolate intermediate. The structure of ...