The biochemical functions of proteins invariably involve interactions with ligands of some type, which act as enzyme substrates or inhibitors, signaling molecules, allosteric modulators ...

This review examines the impact of liver immune responses, as triggered by the intestinal microbiota, on the activity of drug-metabolising enzymes and discusses the implications for precision ... and ...

THE exact intermediate steps in the breakdown caused by ribonuclease enzymic activity awaits clarification in spite of the many methods currently used in the measurement of ribonuclease activity.

This manuscript provides fundamental studies to help us better understand the effects of mutations in the presenilin-1 (PSEN1) gene on proteolytic processing of the amyloid precursor protein (APP).

Effects of FAD-mutant PSEN1 on endoproteolysis of C99 by γ-secretase. (A) Diagram of proteolytic cleavage of APP substrate by γ-secretase via two pathways. (B) Ribbon diagram of APP substrate bound to ...

Enzymes that catalyze oxygenation of a single substrate at different positions were differently inhibited by various ... As previously reported from our isotope feeding experiments, it is expected ...

Edited by Éva Kondorosi, Hungarian Academy of Sciences, Biological Research Centre, Szeged, Hungary; received March 26, 2024; accepted October 7, 2024 ...

"Enzyme Substrates market Expands Due to Rising Biotechnological Innovations and Growing Applications in Pharmaceuticals, Food, and Environmental Industries." AUSTIN, TX, UNITED STATES, October 29 ...