Investigating new treatments for rare skin lymphomas
A fusion protein therapy may be an effective treatment option for cutaneous T-cell lymphomas, according to a multicenter ...
Nature5 年
Developing isogenic cell models with CRISPR: an EML4-ALK fusion NSCLC cell line
An isogenic cell line was created to model cancer patients with the echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusion oncogene and tested for its ...
Nature1 年
Detection of protein-protein interactions using the GST fusion protein pull-down technique
Because the aim of the experiment is to compare GST with a GST fusion protein, it is necessary to prepare enough precleared lysate for each reaction. Efficient mixing of reagents is the key to ...
ophthalmologytimes3 天
Ocugen doses first patient in phase 1 trial of OCU200 for treatment of diabetic macular edema
The phase 1 clinical trial is a multicenter, open-label, dose-escalation study to assess drug safety via intravitreal ...
BioWorld3 天
New granzyme B-based immunotoxin targeting breast cancer, including TNBC
Researchers have developed an innovative immunotoxin (a fusion protein called GrB-Fc-KS49) designed to target epithelial membrane protein-2 (EMP2), a biomarker overexpressed in more than 75% of breast ...
Vera Therapeutics: Strategic Licensing and Promising Clinical Data Justify Buy Rating
Rami Katkhuda, an analyst from LifeSci Capital, maintained the Buy rating on Vera Therapeutics (VERA – Research Report). The associated price ...
BioWorld1 个月
CO-005 is potent new anti-CD47 fusion protein
Researchers from Caedo Oncology AS presented the discovery and preclinical characterization of CO-005, a novel anti-CD47 fusion protein being developed for the treatment of lymphoma. BioWorld Science ...