In both pediatric and adult patients, cranial radiation therapy causes a debilitating cognitive decline ... induced decrease in postnatal hippocampal neurogenesis. Here we show that the deficit ...

Importantly, new neurons play a role in hippocampus-dependent learning and ... This might be particularly critical for aging-linked cognitive decline, such as occurs in Alzheimers disease.

As early as the 1960s, Altman and Das provided good evidence for neurogenesis in the adult rat hippocampus, and in 1967 the same authors, moved beyond 'evidence' and presented a paper simply ...

Understanding how new neurons affect brain function throughout adulthood can offer new approaches to treating epilepsy and dementia.

During the complex operations, the neurosurgeons carefully removed the affected hippocampus in ... cellular evidence of how neurogenesis contributes to human cognition—in this case, verbal ...

They discovered that fewer new neurons in the hippocampus correlate with a marked decline in verbal learning and memory capabilities. This discovery opens new avenues of hope. Researchers believe ...

One major brain structure in which neurogenesis occurs in adults is the hippocampus, which plays an important role in learning and memory. Can you increase neurogenesis in adulthood? Created with ...

The widespread presence of estrogen receptors in many regions involved in cognitive processes (such as learning and memory) including the hippocampal formation (HF), amygdala and cerebral cortex ...

the rats completed a number of behavioral tests to assess their cognitive abilities. After this, researchers euthanized the rats and analyzed their tissue to assess hippocampal neurogenesis.