National Cancer Institute researchers have developed a method called HORNET for characterizing 3D topological structures of large and flexible RNA molecules. Scientists used atomic force microscopy ...
High-throughput DNA sequencing techniques enable time- and cost-effective sequencing of large portions of the genome. Instead of sequencing and annotating whole genomes, many phylogenetic studies ...
Identification of pathogenic DNA sequence alterations in patients with ... greater than 12 base pairs and alterations spanning an intron-exon border. Also, analysis of non-exonic alterations ...
In many organisms, aging is a clear risk factor for increased rates of chromosome mis-segregation, the main source of aneuploidy. Here, we report that old yeast mother c ...
The eukaryotic DNA sequence is composed of a certain number of exons and introns. During transcription of one gene, exons will be kept and assembled together, while introns will be cut liking the ...
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Sequence motifs are becoming increasingly important in the analysis of gene regulation. How do we define sequence motifs, and why should we use sequence logos instead of consensus sequences to ...
SEQUENCE AND RESTRICTION SITE ANALYSIS OF THE GTP-CH-I GENE Genomic DNAs were extracted from peripheral blood leucocytes of the eight patients, their parents, and 50 unrelated normal control subjects.
The evolution of life is marked by the emergence of novel traits, driven by the birth of new genes. This process of genetic ...
The splicing process is performed by the spliceosome that assembles around splice sites at each intron. Depending on how far their sequences diverge from the consensus sequence, defines the strength ...
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