Three people with type 1 diabetes who received Vertex Pharma’s islet cell therapy VX-880 have been ... reduction of haemoglobin A1c levels – a marker of blood glucose control – to 7% or ...

Case 1 suggests that ICA may be a transient marker of a persisting underlying ... indicate inevitable progression to total islet cell destruction and that cessation of immune islet cell ...

Nat Clin Pract Endocrinol Metab. 2006;2(5):240-241. Diabetes occurs when there is an inadequate functional mass of insulin-producing pancreatic β cells. Replacement of β cells by islet ...

The following is a summary of “Identification of a pancreatic stellate cell gene signature and lncRNA interactions associated ...

During islet development, beta-cell death, rather than proliferation alone, regulates beta-cell mass and shapes the immune ...

Risk for pancreatitis was not elevated among users of tirzepatide relative to placebo, despite the presence of elevated pancreatic enzymes.

First-in-Human Study Provides Evidence that Sana’s Hypoimmune (HIP) Technology Enables Transplanted Islet Cells to Avoid Immune Rejection ... of Consistent Levels of Circulating C-Peptide, a Marker of ...

Sana Biotechnology said a type 1 diabetes (T1D) patient received an allogeneic primary islet cell transplantation without ...

PDX-1 is a critically important transcription factor for the insulin promoter, is absent in glucotoxic islets, and, when transfected into glucotoxic ß-cells ... of elevated markers of oxidative ...