Predictive medicine is a branch of medicine that aims to identify patients at risk of developing a disease, thereby enabling either prevention or early treatment of that disease. Either single or ...
Regenerative medicine is the branch of medicine that develops methods to regrow, repair or replace damaged or diseased cells, organs or tissues. Regenerative medicine includes the generation and ...
KRAS基因突变在胰腺导管腺癌(PDAC)中的高频出现,使其成为研究人员梦寐以求的靶点。然而,这一领域长期以来被视为“不可成药”(undruggable)的难题。随着新技术和新思路的涌现,靶向KRAS的治疗正逐渐成为攻克PDAC的重要突破口。
Pharmacogenomics. 2014;15(11):1507-1518. MEK/CDK4 PD-0325901 (MEKi) + palbociclib (CDK4i) NCT02022982 MEK/CDK4 Trametinib (MEKi) + palbociclib (CDK4i) NCT02065063 ...
In KRAS, the variations at codons 12 and 13, which are the most frequent mutations associated with this protein, result in G12D and G13D substitution, respectively. Similarly, the most common mutation ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The adoptive transfer of TCR-T cells specific ...
As Medscape marks its 30th anniversary, we are collaborating with physicians, scientists, and futurists from around the globe to boldly envision the future of medicine in the year 2050.
If approved, the avutometinib-defactinib combination would become the first treatment specifically indicated for low-grade serous ovarian cancer and the first treatment for KRAS-mutant ovarian cancer.
This article discusses eight natural remedies for depression to consider. The herb St. John's wort (Hypericum perforatum) has long been used in folk medicine for treating depression, worry, ...
Revolution Medicines Inc. has synthesized macrocyclic compounds acting as GTPase KRAS, NRAS, HRAS and their mutant inhibitors reported to be useful for the treatment of cancer. BioWorld Science Cancer ...
There is an ever-growing list of the benefits of natural prescriptions – now researchers say nature could offer a cure for loneliness too. Kye Aziz didn't consider himself a big nature lover.