This may also result in significant adverse effects, including electrolyte imbalance, ototoxicity, and volume contraction. Prolonged use of loop diuretics may lead to loop diuretic resistance ...

Future Cardiol. 2012;8(5):707-728. These data come from reports of ototoxicity of 6.4% with furosemide compared with 1 and <1% for bumetanide and torsemide, respectively. [38] Acute kidney failure ...

Bumetanide, a loop diuretic, inhibits sodium reabsorption ... Avoid probenecid, indomethacin. Ototoxicity may be potentiated with aminoglycosides.