Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

Thousands of treated patients support the potential of phage therapy, but limited knowledge of this technique and its ...

The bacterial cell wall is crucial to maintain viability. It has previously been suggested that Gram-positive bacteria have a periplasmic region between the cell membrane and peptidoglycan cell wall ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Impaired insulin receptor signaling is ...

Float scores are based on creative design, floral craftsmanship, artistic merit, computerized animation, thematic interpretation, floral and color presentation, and dramatic impact. Judges ...

LaMelo Ball's days with the Hornets could be numbered if they land the right pick in the 2025 NBA Draft. Dec 23, 2024; Charlotte, North Carolina, USA; Charlotte Hornets guard LaMelo Ball (1) warms ...

A celebration of the queen of crime writers and her most famous characters.

Zosha Millman (she/her) manages TV coverage at Polygon as an entertainment editor, but will happily write about movies, too. She’s been working as a journalist for more than 10 years. I won’t ...

China claims to have achieved a ‘world record’ in shipbuilding by developing a massive cargo ship similar to its Fujian aircraft carrier. Named Fan Zhou 8, the cargo ship has an unprecedented ...

Exciting findings from CUNY researchers reveal a novel target in the fight against Alzheimer’s — harmful microglia activated by cellular stress. This could lead to therapies that reverse the damaging ...

20 times actors passed up on what became iconic roles Stephen Hawking's eerie alien theory might explain why we've never been contacted Beloved all-Italian butchery to close in Kogarah after more ...