The design of tolerogenic vaccines vary greatly, but they all deliver a disease-relevant antigen with or without a tolerogenic adjuvant. Tolerogenic adjuvants are molecules which mediate ...

Maple Leafs winger Max Pacioretty has done it again, absolutely decking Stars forward Mavrik Bourque with a nasty hit, drawing a penalty in the process. The Toronto Maple Leafs are in Dallas on ...

They analyzed results from 878 patients, 43% of whom received adjuvant tamoxifen. After a median follow-up of almost 15 years, 117 cases of ipsilateral (same breast) recurrence were diagnosed. The ...

As with iDFS and DDFS, the OS benefit was consistent across all subgroups. “These data continue to support adjuvant olaparib as standard of care for patients with BRCA+ high-risk HER2-negative primary ...

SHR-A1811 showed promising antitumor activity and acceptable tolerability in patients with HER2-positive breast cancer, according to results of the phase 2 FASCINATE-N trial. The third-generation ...

Phase II Study of Acalabrutinib, Venetoclax, and Obinutuzumab in a Treatment-Naïve Chronic Lymphocytic Leukemia Population Enriched for High-Risk Disease The ESPAC4 trial showed that adjuvant ...