The investigational anti-PD-1 monoclonal antibody is showing positive topline results from the phase 3 CREST trial.

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

Despite recent therapeutic breakthroughs, cancer patients continue to face high recurrence and mortality rates due to treatment resistance. Cancer stem cells (CSCs), a subpopulation with self-renewal ...

T-Mobile is the third-largest wireless carrier in the United States, with its popularity largely down to its network coverage and the wide range of tempting offers available. They span from T ...

It can also describe other toxins like venom from snakes. The human immune system even has cells that are cytotoxic: T-cells kill bacteria, viruses, and cancer cells. This article will go over the ...

Researchers have created a way to guide and control the development of stem cells into specific tissues ... in ways that traditional approaches can’t, they’re a foundation for how diseases ...

Based on this evidence, we defined clusters 1 and 2 as naive T, three as regulatory/exhausted T, and 4 & 5 as cytotoxic T cells. Intriguingly, regarding both the sample origins and expression profiles ...

Aging alters the immune environment of the heart by concomitantly driving the changes in immune cell metabolism, mitochondrial dysfunction, and redox signaling. Shifts in these metabolic pathways ...

Professor Kwang-Hyun Cho remarked, "The fact that cancer cells can be converted back to normal cells is an astonishing phenomenon. This study proves that such reversion can be systematically induced." ...

Sophisticated diversification seeks to maximize gains and minimize risks but isn't always effective. Complex models often have unknown variables and estimation errors, making naive diversification ...

At the end of 2012, T-Mobile US was not in a good place ... Things like: could we be the first to provide direct-to-cell service, working with SpaceX, so that we can have the end of dead zones ...