Thus, both oxidative and genotoxic stress signalling ... Importantly, both FoxO and TSC2 are biochemically and genetically linked to PI3K–AKT/PKB signalling (see figure, right panel).

Enhancing anti-oxidant and anti-inflammatory effects and activating PI3K/Akt were the mechanisms that mediated this effect.

In Lag3-mutated Tregs, the scientists found that increased expression of Myc and downstream pathways, including the PI3K-Akt-Rictor pathway ... rather than utilizing oxidative phosphorylation ...

Neuroinflammation drives the progression of neurodegenerative disorders like Alzheimer's, Parkinson's, and multiple sclerosis. Targeting neuroinflammation with small molecules is promising, but ...

A recent study published in Antioxidants highlights the protective benefits of microalgae extract and phytoene, showing they reduce oxidative stress, combat beta-amyloid toxicity, and extend ...

Are mango leaves good for health? Yes! Rich in antioxidants, mango leaves may help with diabetes, fat metabolism, and even ...

Enhancing anti-oxidant and anti-inflammatory effects and activating PI3K/Akt were the mechanisms that mediated this effect.

Today, Pacylex announced the publication of a new study in Molecular Cancer Therapeutics, "Zelenirstat Inhibits N-Myristoyltransferases to Disrupt Src Family Kinase Signaling and Oxidative ...

Expert Rev Clin Pharmacol. 2012;5(3):319-336. Finally, a recent study suggested that although prasugrel significantly reduces thrombotic events in patients with ACS undergoing PCI because of its ...

(A) Experimental design of the in vivo study. (B) The embryo implantation status. (C) Morphology of follicles and granulosa cells as detected by HE. (D)The MDA levels in ovary. (E) The SOD levels ...

Investigation on anti-diabetic efficacy of a Cucurbitaceae food plant from the North-East region of India: Exploring the molecular mechanism through modulation of oxidative stress and glycosylated ...