Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China University of Chinese Academy of Sciences, No. 19A ...

This study presents the state-dependent role of serotonin for the protein and sugar intake of Drosophila by expressing a dominant-negative serotonin transporter in subsets of serotoninergic neurons.

However, it is particularly difficult to maintain the original structure and cell composition ... including Bruton's tyrosine kinase (BTK) inhibitors, PI3K inhibitors, and BCL-2 inhibitors ...

Other promising players in the oral obesity space include Viking Therapeutics, which is advancing the GLP-1/GIP agonist VK2735, and Structure Therapeutics, which is running a md-stage study of its ...

It is made of dead, flattened cells called keratinocytes that are shed approximately two weeks after they enter this layer. Keratinocytes produce keratin, a fibrous protein that helps provide ...

Most cells form large vesicles of 350–600 nm in diameter at their apical side, continuously internalizing their surrounding medium. Macropinocytosis was confirmed using specific inhibitors of PI3K and ...

Capital structure is the mix of debt and equity that fund a company's operations. A judicious use of debt and equity is a key indicator of a strong balance sheet. A healthy capital structure that ...