Oncolytic adenoviruses were designed to reach potent intratumoral T-cell activation via expression of bifunctional-T-cell ...

2019). NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor. PHGDH catalyzes the first step in the de novo synthesis of L-serine from 3-phosphoglycerate. It has been identified as an ...

This is a useful study that adds new data to how different DAG pools influence cellular signaling, and dissects how the enzyme Dip2 modulates the minor lipid signaling DAG pool, which is distinct from ...

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Department of Oral Anatomy and Physiology, Jilin Provincial Key Laboratory of Oral Biomedical Engineering, Hospital of Stomatology, Jilin University, Changchun, China Oral squamous cell carcinoma ...

Department of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208, United States Center for Synthetic Biology, Northwestern University, Evanston, Illinois 60208, ...