Direct translocation of RNA with secondary structures using single-molecule electrophoresis through protein nanopores shows significant fluctuations in the ... In the slow mode, the molten globule ...

Combining interactome analysis with genome editing, we further uncover the RNA-binding protein ELAV-like protein 1 (ELAVL1 ... Remarkably, MS-444 treatment potently reduced the constitutive secretion ...

A C-reactive protein test (CRP) is a blood test that detects general inflammation in the body ... A test called a high-sensitivity CRP (hs-CRP) test can be used in people with risk factors for heart ...

(2) The authors observe by cryoEM three distinct states of this spliceosome, each distinguished from the next by progressive loss of protein factors and/or RNA residues. The authors appropriately ...

This important study addresses how 3' splice site choice is modulated by the conserved spliceosome-associated protein Fyv6. The authors provide compelling evidence that Fyv6 functions to enable ...

X-Box binding protein 1; ANRIL, Antisense Non-Coding RNA in the INK4 Locus; HUVECs, human umbilical vein endothelial cells; CAD, coronary artery disease; lncR-GAS5, long non-coding RNA growth ...

Translation entails ribosomes reading a gene’s messenger RNA transcript to generate a protein. Image credit: ART-ur/ Shutterstock ... This, Mendell says, “proved that the tRNA was the determining ...

It is regulated by variation in the concentration of cleavage and polyadenylation factors and by RNA-binding proteins, as well as by splicing and transcription. APA is important for cell ...

Nuclear-encoded genes are necessary for the expression of mitochondrial genes, including transcription, pre-mRNA processing, translation of the mRNAs into mitochondrial proteins ... progress on the ...