As many as half of the disease-associated single-nucleotide mutations in the coding regions of genes do not alter specific amino acids in the protein, but rather affect RNA splicing; for example ...

DYNE-101 eased myotonia and led to other functional improvements for people with myotonic dystrophy type 1 (DM1) in a ...

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing ...

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other ...

A research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as ...

This mutation resides within the TBXT gene ... resulting in the removal of an entire exon during RNA splicing.

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington’s disease and link HD with other ...

The platform enables access to a comprehensive range of next generation sequencing (NGS) DNA and RNA data, including sequencing quality control, detected DNA and RNA variants, tumor mutation ...