Columnist Oluwatosin Adesoye shares a list of things that everyone should know and understand about sickle cell disease.

There are many types of sickle cell disease. The majority of cases are divided into three subtypes depending on which genes you inherited: Hemoglobin is an iron-containing protein found in your ...

More than 500,000 babies were tested for sickle cell disease in Catalonia’s newborn screening program, with 160 cases ...

In sickle cell disease, a gene mutation causes the hemoglobin molecules in red blood cells to form a rigid chain. This causes the cells to stiffen into a sickle shape, clogging blood vessels and ...

Gene-editing kicked off 2024 with a bang in the medical sector but closed the year with a whimper. It started with the FDA ...

They didn’t know that she carried a genetic blueprint for a misshapen molecule; that her hemoglobin proteins ... newborn’s heel and test it for sickle cell disease. Catch it early and you ...

The following is a summary of “Safety and efficacy of mitapivat in sickle cell disease (RISE UP): results from the phase 2 ...

Hydroxyurea showed more dose-limiting toxicities than placebo but reduced clinical AEs and improved hematological parameters, ...

Treatments for rare diseases are hard to create and expensive to deliver, but there is new hope for editing the software of ...

“Sickle cell disease (SCD) has a broad spectrum of ... instructions for his red blood cells to make a fetal form of hemoglobin. (Unlike “adult” hemoglobin, fetal hemoglobin doesn’t cause ...

The new gene therapies for sickle cell disease—including the gene-editing ... that raises fetal hemoglobin levels. The FDA approved it in 1998. But Orkin says hydroxyurea and other available ...