Important genes involved in the lipid-lowering response to statin therapy include the HMGCR and APOE genes. However, those results are equivocal and further studies are needed to explore the role ...
DRB1*11:01 was associated with an increased risk of anti-HMGCR myopathy. This study, therefore, suggests a mechanistic link between statin exposure, increased HMGCR expression and the potential ...
Statins are the most widely prescribed, cholesterol-lowering drugs in the world. Despite the expiration of their patents, revenue for statins is expected to rise, with total sales on track to reach an ...