Mutations in NPC1 cause Niemann-Pick Type C. Mice lacking NPC1 only in microglia have rampant neuroinflammation and impaired ...

First subjects dosed in a Phase 2 trial of VTX3232 in participants with obesity and cardiometabolic risk factors, with topline data expected in ...

Research indicates smoking may improve cognitive control in HIV-positive individuals by lowering brain inflammation, ...

虽然这项研究提供了证据表明吸烟可能通过减轻神经炎症来改善HIV感染者的认知表现，但它并不支持吸烟作为治疗手段。长期吸烟的危害远远超过其任何可能的好处。因此，这项研究的主要价值在于提示了未来可能用于缓解神经炎症的新途径。

Inflammatory responses are closely associated with many neurologic disorders and influence their outcome. In vivo imaging can document events accompanying neuroinflammation, such as changes in blood ...

It is administered through oral route. It is developed based on allosteric modulation technology. It acts by targeting GABAA receptors and TSPO. D-etifoxine is a new chemical entity (NCE). It was also ...

It is administered through oral route. It is developed based on allosteric modulation technology. It acts by targeting GABAA receptors and TSPO. D-etifoxine is a new chemical entity (NCE). It was also ...

Our search terms (see online supplementary appendix 1 for further details) were the following: (inflammat* or cytokine or interferon or IFN or interleukin or ‘translocator protein’ or TSPO or ‘tumour ...

Intracellular lipid transport can occur by flip‐flop from one side of a bilayer to the other, by vesicular trafficking, by lipid transfer proteins, or by diffusion within a bilayer 34. MAMs are hubs ...

Acute pancreatitis (AP) is an inflammatory disease of the pancreas and a complex process involving multiple factors, with mitochondrial damage playing a crucial role. Mitochondrial dysfunction is now ...

1 Department of Neurology, Huashan Hospital, Fudan University and Institute of Neurology, Fudan University, National Center for Neurological Disorders, Shanghai, China 2 Department of Neurological ...