Thymidine analog-associated mutation-containing ... ide analog reverse-transcriptase inhibitor monophosphate (red) is removed from the end of terminated DNA (bottom). The most likely pyrophosphate ...

To examine the roles of IMPL1 and IMPL2 enzymes, we expressed and purified recombinant IMPL1 and IMPL2 proteins. Both genes encode putative chloroplast transit peptides, as predicted by alignment of ...