Here the authors show structures of the vesicular acetylcholine transporter in its apo state ... Multidrug resistance-associated protein 2 (MRP2) is an ATP-powered multidrug exporter.

These effects are primarily caused by the IGF2 receptor, which is widely expressed in neurons and controls protein trafficking, synthesis ... in AD is a reduction in cholinergic neurotransmission ...

Researchers at the University of Adelaide have discovered that a protein which mediates the transport of alkali metal ions, such as potassium, and halides ions across plant membranes acts similarly to ...

The research, which made use of large-scale bioinformatics with ancestral sequence reconstruction, 3D protein modeling, and transport thermodynamics, will allow plant breeders to understand how ...

In this special issue of Research Topic, authors focus on the significance of non-neuronal acetylcholine (NNA) in the cardiovascular system under different physiological and pathological conditions ...

This fundamental work provides evidence that glutamate and GABA are released from different synaptic vesicles at supramammillary axon terminals onto granule cells of the dentate gyrus. The study uses ...

We speculate the increase in KCNQ2 abundance is a compensatory mechanism that does not achieve to restore the function of the cell. This experiment assessed total protein abundance, which includes ...