Liver cells attempt to shut down as a defense mechanism against cancer, but this strategy is not particularly effective.

A new study reveals that certain diets, particularly those high in fat and sugar, could significantly increase the risk of ...

Medically reviewed by Robert Burakoff, MD The liver is an extraordinary organ with a remarkable ability to heal and ...

Scientists at University of California San Diego School of Medicine have shed new light on the development of liver cancer, ...

Lithocholic acid (LCA), a metabolite induced by calorie restriction (CR), activates AMPK and mimics anti-aging benefits. A ...

The six subunit ORC is essential for initiation of DNA replication in eukaryotes. Cancer cell-lines in culture can survive and replicate DNA replication after genetic inactivation of individual ORC ...

The accumulation of lipids in hepatocytes in nonalcoholic fatty liver disease (NAFLD) leads to an increase in reactive oxygen species and changes in the intracellular microenvironment, while ...

Figure 1: a, Schedule of DMN administrations and HGF–HVJ liposome or PBS injections. Figure 3: a–c, Liver sections of rats after DMN administration. Sprague–Dawley rats 4–5 weeks old and ...

Here we reexamine the impact of endurance training on norepinephrine-stimulated gluconeogenesis in the absence of any other hormones. Isolated hepatocytes from trained and untrained rats were ...