Bladder cancers comprise heterogeneous cell populations, and numerous factors are likely to be involved in dictating recurrence, progression and patient survival. While several molecular markers ...

Our vision is to innovate and incorporate promising technologies to communicate freely available, high-priority, high-quality content, which accelerates scientific progress and advances heart and ...

The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic ...

In human tumours, interrupting cytokine-driven signalling loops has been achieved in two ways: first, through downregulation of the IGFBP7 gene promoter by hypermethylation 12; second, through a ...

Correspondence to Dr Hidenobu Soejima, Division of Molecular Genetics & Epigenetics, Department of Biomolecular Sciences, Saga University Faculty of Medicine, Saga 849-8501, Japan; soejimah{at}cc.saga ...

This important study presents a significant methodological advance by leveraging previously discarded, unmapped DNA sequence reads to estimate pest infestation loads across plant accessions, and map ...

The issue of hyperplastic polyps being potential precursors for CRC is an area of controversy, and at this point there are no specific data that demonstrate that hyperplastic polyps can progress ...