New insights about the PDGF/PDGFR signaling pathway as a …
2023年5月1日 · Association of the platelet-derived growth factor and platelet-derived growth factor receptor (PDGF–PDGFR) signaling pathway with tumor progression and metastasis. In …
Targeting the PDGF/PDGFR signaling pathway for cancer …
2022年3月31日 · Activation of the PDGF/PDGFR signaling pathway is associated with cancer proliferation, metastasis, invasion, and angiogenesis through modulating multiple downstream …
Platelet-derived Growth Factor (PDGF) Signaling Pathway
Platelet-derived growth factor receptor (PDGFR) signaling plays a crucial role in specifying mesenchymal stem cell (MSC) commitment to mesenchymal lineages. Platelet-derived growth …
Targeting the PDGF/PDGFR signaling pathway for cancer
2022年3月31日 · PDGF isoforms bind to their related PDGFRs, initiate distinct receptor dimerization and phosphorylation, and provide multiple binding sites for the downstream …
Platelet-derived growth factor (PDGF) signalling in cancer: …
Platelet-derived growth factor (PDGF)-mediated signalling has emerged as one of the most extensively and deeply studied biological mechanism reported to be involved in regulation of …
New insights about the PDGF/PDGFR signaling pathway as a …
By directly stimulating tumour cells in an autocrine manner or by stimulating tumour stromal cells in a paracrine manner, the platelet-derived growth factor (PDGF)/platelet-derived growth factor …
Targeting the PDGF signaling pathway in tumor treatment
Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may …
Role of platelet-derived growth factors in physiology and …
Autocrine activation of PDGF signaling pathways is involved in certain gliomas, sarcomas, and leukemias. Paracrine PDGF signaling is commonly observed in epithelial cancers, where it …
Emerging roles of PDGF-D signaling pathway in tumor …
Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may …
Current status of drugs targeting PDGF/PDGFR - ScienceDirect
2024年7月1日 · Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D …