Antifungals: What They Treat, How They Work & Side Effects
2021年7月26日 · Antifungal medications treat fungal infections that affect the skin, nails, lungs and other organs. Some fungal infections clear up in a few weeks. Others may need months of treatment. Taking antifungal medicines for an extended period or failing to complete the prescribed treatment may lead to antifungal resistance.
Antifungal drugs: Types, uses, when to seek help - Medical News Today
2021年7月7日 · Antifungal drugs are the medications people use to treat fungal infections. People can take antifungal drugs orally, apply them topically, or administer them intravenously...
Antifungal Medications: What You Should Know - Verywell Health
2024年3月3日 · Antifungal drugs are a class of medications that are used to treat invasive fungal infections. There is a wide range of types, strengths, formulations, and uses for the medications in this class. Each of these medications works by killing fungi-causing infection and/or stopping the fungi from continuing to grow.
Antifungal Drugs - PMC - National Center for Biotechnology …
2020年3月12日 · We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi. Approved antimycotics inhibit 1,3-β-d-glucan synthase, lanosterol 14-α-demethylase, protein, and deoxyribonucleic acid biosynthesis, or sequestrate ergosterol. Their most severe side effects are ...
Antifungal Antibiotics - StatPearls - NCBI Bookshelf
2023年3月7日 · Antifungal antimicrobials are one drug class that can combat these mycoses. This activity reviews the indications, contraindications, activity, adverse events, and other critical elements of antiemetic use of antifungal antimicrobials in the clinical setting as relates to the essential points needed by members of an interprofessional team ...
Antifungal Drugs - PubMed
2020年3月12日 · We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi. Approved antimycotics inhibit 1,3-β-d-glucan synthase, lanosterol 14-α-demethylase, protein, and deoxyribonucleic acid biosynthesis, or sequestrate erg ….
Antifungal Medications - Antifungal Medications - The Merck …
These drugs are potently fungicidal against most clinically important Candida species (see treatment of invasive candidiasis) but are considered fungistatic against Aspergillus. Adverse effects of echinocandins include hepatitis and rash.
Molecular mechanisms governing antifungal drug resistance
2023年7月17日 · In this review, we discuss the diverse strategies employed by leading fungal pathogens to evolve antifungal resistance, including drug target alterations, enhanced drug efflux, and induction...
Tackling the emerging threat of antifungal resistance to human …
2022年3月29日 · Resistance to antifungal drugs is an emerging concern worldwide in both space and time 4, including novel resistant variants of previously susceptible pathogens (for example, the ubiquitous...
Advances in Antifungal Drug Development: An Up-To-Date Mini …
2021年12月16日 · Novel antifungals in clinical development include first-in-class agents, new structures for an established target, and formulation modifications to marketed antifungals, in addition to repurposed agents. Membrane interacting peptides and aromatherapy are gaining increased attention in the field.