KEGG PATHWAY Database
2024年12月26日 · KEGG PATHWAY is a collection of manually drawn pathway maps representing our knowledge of the molecular interaction, reaction and relation networks for:
DNA choreography: correlating mobility and organization of DNA …
2024年5月17日 · The dynamics of DNA in the cell nucleus plays a role in cellular processes and fates but the interplay of DNA mobility with the hierarchical levels of DNA organization is still underexplored. Here, we made use of DNA replication to directly label genomic DNA in an unbiased genome-wide manner.
Mobility and Repair of Damaged DNA: Random or Directed? - Cell …
New cell biology approaches have indicated that damaged DNA mobility exhibits random and directed movements during DNA repair. Here, we review recent studies that collectively reveal that cooperation between different molecular mechanisms, which underlie increases in the random and directional motion of damaged DNA, can promote genome repair.
Polymer perspective of genome mobilization - PMC - National …
While the exact mechanism is unknown, overall increased motility at certain loci in haploids may facilitate HR following DNA damage, whereas less motility is needed in homologous chromosome-containing diploids. Processes that rely on ATP, such as ATP-dependent chromatin remodelers, also impact the motility of DNA.
Polymer perspective of genome mobilization - ScienceDirect
2020年5月1日 · While the exact mechanism is unknown, overall increased motility at certain loci in haploids may facilitate HR following DNA damage, whereas less motility is needed in homologous chromosome-containing diploids. Processes that rely on ATP, such as ATP-dependent chromatin remodelers, also impact the motility of DNA.
KEGG PATHWAY: Cell cycle - Homo sapiens (human) - GenomeNet
Mitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cyclin-dependent kinases (CDKs) are key regulatory enzymes, each consisting of a catalytic CDK subunit and an activating cyclin subunit.
7.25E: DNA Mobility Shifts - Biology LibreTexts
2024年11月23日 · The interaction of proteins with DNA is central to the control of many cellular processes, including DNA replication, recombination and repair, transcription, and viral assembly. An advantage of studying protein-DNA interactions by an electrophoretic mobility shift assay is the ability to resolve complexes of different stoichiometry or ...
Electrophoretic Mobility of DNA in Solutions of High Ionic Strength
2020年6月2日 · The free-solution mobilities of small single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) have been measured by capillary electrophoresis in solutions containing 0.01–1.0 M sodium acetate. The mobility of dsDNA is greater than that of ssDNA at all ionic strengths because of the greater charge density of dsDNA.
Mapping DNA Quantity into Electrophoretic Mobility through …
2012年1月1日 · Intuitively, the greater the number of conjugated DNA molecules, the faster the nanoassemblies migrate, thereby mapping DNA quantity into an electrophoretic mobility shift. To perform QEMSA, biotin-tagged DNA fragments are generated and duplicated from target gene sequences of genomic DNA using biotinylated probes.
Motifmap
MotifMap: genome-wide maps of regulatory elements. The MotifMap system provides comprehensive maps of candidate regulatory elements encoded in the genomes of model species using databases of transcription factor binding motifs, refined genome alignments, and a comparative genomic statistical approach- Bayesian Branch Length Score.