Diphtheria antitoxin - Wikipedia
Diphtheria antitoxin (DAT) is a medication made up of antibodies used in the treatment of diphtheria. [ 1 ] [ 2 ] It is no longer recommended for prevention of diphtheria. [ 2 ] [ 3 ] It is administered through injection into a vein or muscle .
Diphtheria Antitoxin - CDC
2024年12月18日 · Diphtheria antitoxin (DAT) has been used for decades to treat diphtheria but is no longer produced in the United States. The Food and Drug Administration (FDA) has authorized CDC to distribute DAT as an expanded access investigational new drug (EA-IND).
Diphtheria antitoxin (injection route) - Mayo Clinic
2024年1月31日 · Diphtheria antitoxin is used to prevent and/or treat diphtheria infection in persons exposed to the disease. Although rare in the U.S., diphtheria is a serious disease that can cause life-threatening illnesses. Diphtheria is transmitted through contact with an infected person or a carrier of the disease.
Diphtheria - Diagnosis & treatment - Mayo Clinic
2023年10月6日 · An antitoxin. If a doctor suspects diphtheria, he or she will request a medication that counteracts the diphtheria toxin in the body. This medication comes from the Centers for Disease Control and Prevention. Called an antitoxin, this drug is injected into a vein or muscle. Before giving an antitoxin, doctors may perform skin allergy tests.
Clinical Guidance for Diphtheria - CDC
2024年2月12日 · Antitoxin. Respiratory diphtheria: Diphtheria antitoxin (DAT) is recommended. Cutaneous diphtheria: Antitoxin isn't typically needed. In the United States, healthcare providers can obtain diphtheria antitoxin from CDC on request.
Diphtheria - StatPearls - NCBI Bookshelf
2024年2月26日 · Diphtheria antitoxin (DAT), derived from horse antiserum, is crucial in treatment. Antitoxin functions by neutralizing unbound diphtheria toxin circulating in the blood. The antitoxin becomes ineffective once the toxin has bound to the cell membrane.
investigational diphtheria antitoxin (DAT) for treatment of suspected diphtheria cases, and for prophylactic use under exceptional circumstances in an exposed contact, in the absence of Food and Drug
Diphtheria Antitoxin Monograph for Professionals - Drugs.com
2024年8月22日 · Diphtheria antitoxin (equine) is a sterile solution of refined and concentrated protein (mainly immunoglobulins) containing antitoxic antibodies prepared from the serum of horses hyperimmunized with diphtheria toxoid. Uses for Diphtheria Antitoxin. Diphtheria antitoxin (equine) is used in the treatment of probable or confirmed diphtheria.
Diphtheria antitoxin Advanced Patient Information - Drugs.com
2024年10月2日 · Diphtheria antitoxin is used to prevent and/or treat diphtheria infection in persons exposed to the disease. Although rare in the U.S., diphtheria is a serious disease that can cause life-threatening illnesses.
Diphtheria antitoxin (DAT) is a product which neutralizes the circulating toxin and is critical in preventing the life-threatening manifestations of diphtheria in addition to antibiotics which eliminate the bacteria and stop toxin production. DAT is based on horse serum and therefore, although rare, severe and immediate anaphylaxis is a risk.