Diphtheria antitoxin - Wikipedia
Diphtheria antitoxin (DAT) is a medication made up of antibodies used in the treatment of diphtheria. [ 1 ] [ 2 ] It is no longer recommended for prevention of diphtheria. [ 2 ] [ 3 ] It is administered through injection into a vein or muscle .
Diphtheria Antitoxin - CDC
Dec 18, 2024 · Diphtheria antitoxin (DAT) has been used for decades to treat diphtheria but is no longer produced in the United States. The Food and Drug Administration (FDA) has authorized CDC to distribute DAT as an expanded access investigational new drug (EA-IND).
Diphtheria antitoxin (injection route) - Mayo Clinic
Jan 31, 2024 · Diphtheria antitoxin is used to prevent and/or treat diphtheria infection in persons exposed to the disease. Although rare in the U.S., diphtheria is a serious disease that can cause life-threatening illnesses. Diphtheria is transmitted through contact with an infected person or a carrier of the disease.
Diphtheria - Diagnosis & treatment - Mayo Clinic
Oct 6, 2023 · Antibiotics, such as penicillin or erythromycin, help kill bacteria in the body, clearing up infections. Antibiotics lessen the time that someone with diphtheria is contagious. An antitoxin. If a doctor suspects diphtheria, he or she will request a medication that counteracts the diphtheria toxin in the body.
Clinical Guidance for Diphtheria - CDC
Feb 12, 2024 · Antitoxin. Respiratory diphtheria: Diphtheria antitoxin (DAT) is recommended. Cutaneous diphtheria: Antitoxin isn't typically needed. In the United States, healthcare providers can obtain diphtheria antitoxin from CDC on request.
Diphtheria - StatPearls - NCBI Bookshelf
Feb 26, 2024 · Diphtheria antitoxin (DAT), derived from horse antiserum, is crucial in treatment. Antitoxin functions by neutralizing unbound diphtheria toxin circulating in the blood. The antitoxin becomes ineffective once the toxin has bound to the cell membrane.
Diphtheria - World Health Organization (WHO)
Jul 12, 2024 · Cases of diphtheria are usually treated with diphtheria antitoxin as well as antibiotics. Diphtheria specific antitoxin neutralizes circulation toxin in the blood. Detailed instructions for giving antitoxin can be found in the WHO treatment guidelines.
Diphtheria is a clinical syndrome caused by an exotoxin produced by the bacterium Corynebacterium diphtheriae; non-toxin-producing strains of C. diphtheriae are not associated with the syndrome but can cause localized inflammation. Most commonly, toxigenic infection results in respiratory or cutaneous disease.
Diphtheria antitoxin Advanced Patient Information - Drugs.com
Oct 2, 2024 · Diphtheria antitoxin is used to prevent and/or treat diphtheria infection in persons exposed to the disease. Although rare in the U.S., diphtheria is a serious disease that can cause life-threatening illnesses. Diphtheria is transmitted through contact with an infected person or a carrier of the disease.
Diphtheria antitoxin (DAT) is a product which neutralizes the circulating toxin and is critical in preventing the life-threatening manifestations of diphtheria in addition to antibiotics which eliminate the bacteria and stop toxin production. DAT is based on horse serum and therefore, although rare, severe and immediate anaphylaxis is a risk.