ETV1 Gene - GeneCards | ETV1 Protein | ETV1 Antibody
2024年10月1日 · ETV1 (ETS Variant Transcription Factor 1) is a Protein Coding gene. Diseases associated with ETV1 include Skeletal Ewing Sarcoma and Soft Tissue Sarcoma. Among its related pathways are Akt Signaling and MAPK-Erk Pathway.
从基础到临床：ETV1研究进展 - 肿瘤
ETS 变体基因 1（ETS variant gene 1， ETV 1）是一个重要的癌基因，在胚胎发育和肿瘤的恶性进展中扮演了重要角色。. 染色体易位、基因扩增和丝裂原活化蛋白激酶（mitogen-activated protein kinase，MAPK）信号通路的激活都能够引起 ETV1 表达水平的上调，而 ETV1 作为转录 ...
ETV1 - Genecast
ETV1 is a downstream transcriptional mediator of the MAP kinase pathway and it is tightly regulated by the MAP kinase through transcription, protein stability, and phosphorylation. The endogenous expression of ETV1 is restricted to several tissues, including specific neurons of the central and peripheral nervous systems and the interstitial ...
Relationship between ETS Transcription Factor ETV1 and TGF-β
2019年6月3日 · The oncogenic transcription factor ETS variant 1 (ETV1) becomes overexpressed in many prostate tumors by chromosomal translocations involving the ETV1 gene and androgen-responsive promoters 1,...
ETV1 is a lineage survival factor that cooperates with KIT in ...
2010年10月3日 · Transcriptome profiling and global analyses of ETV1-binding sites suggest that ETV1 is a master regulator of an ICC-GIST-specific transcription network mainly through enhancer binding.
ETV1 ETS variant transcription factor 1 [ (human)]
2024年10月10日 · ETV1 and COP1 are a pair of independent predictors of prognosis for triple-negative breast cancer. ETV1 overexpression is associated with prostate cancer aggressiveness. Results show that ETV1 was upregulated at a higher rate in Gastrointestinal stromal tumor and was correlated with KIT expression.
ETV1 activates a rapid conduction transcriptional program in
2018年7月2日 · Etv1 defines progressive maturation of rapid conduction zones in the heart. Specific genetic markers of the HPS have facilitated investigation of the molecular circuitry regulating PC ...
The Transcription Factor ETV1 Induces Atrial Remodeling and …
2018年7月24日 · Our results demonstrate that cardiac myocyte-specific overexpression of ETV1 in the mouse induces atrial arrhythmia, atrial structural, and molecular remodeling. In contrast, cardiac myocyte-specific ablation of ETV1 leads to a …
Genome-wide analysis of ETV1 targets: Insights into the role of ETV1 …
ETS variant 1 (ETV1) is a key player in metastatic progression in several types of human cancers, yet the direct target genes of ETV1 and the mechanisms by which ETV1 exerts its deleterious function remain largely elusive. Here, we performed large-scale mapping and analysis of target loci of ETV1 in ….
Frontiers | ETV1 Positively Correlated With Immune Infiltration and ...
2022年7月3日 · Our study revealed that ETV1 was positively related to immune marker genes of M2 macrophages and CAFs in CRC, indicating that ETV1 may play important roles in regulating CAFs and M2 macrophages to promote colorectal tumorigenesis.