FOXM1 Gene - GeneCards | FOXM1 Protein | FOXM1 Antibody
2024年12月25日 · FOXM1 (Forkhead Box M1) is a Protein Coding gene. Diseases associated with FOXM1 include Hepatocellular Carcinoma and Alagille Syndrome 1. Among its related pathways are Signaling by ALK fusions and activated point mutants and Loss of proteins required for interphase microtubule organization from the centrosome.
Regulation of the master regulator FOXM1 in cancer - PMC
FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the processes of cell proliferation, self-renewal, and tumorigenesis.
FOXM1: A Multifunctional Oncoprotein and Emerging Therapeutic …
2021年6月19日 · As a master transcriptional regulator, FOXM1 promotes critical oncogenic phenotypes in ovarian cancer, including: (1) cell proliferation, (2) invasion and metastasis, (3) chemotherapy resistance, (4) cancer stem cell (CSC) properties, (5) genomic instability, and (6) altered cellular metabolism.
FOXM1: Functional Roles of FOXM1 in Non-Malignant Diseases
FOXM1, another forkhead box gene, is an essential regulator of oxidative stress response and one of the prominent participants in tumorigenesis. It is a leading object of research on the elderly. FOXM1 is a vital transcription factor protein that regulates the cell cycle.
FOXM1 and Cancer: Faulty Cellular Signaling Derails Homeostasis
FOXM1 is highly expressed in several cancers and has also been implicated in poor prognosis. A comprehensive understanding of various aspects of this molecule has revealed its role in angiogenesis, invasion, migration, self- renewal and drug resistance.
Regulation of the master regulator FOXM1 in cancer
2018年9月12日 · FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the processes of cell proliferation, self-renewal, and tumorigenesis.
FOXM1: From cancer initiation to progression and treatment
2012年1月1日 · The Forkhead box protein M1 (FOXM1) transcription factor is a regulator of myriad biological processes, including cell proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue homeostasis, angiogenesis and apoptosis.
2305 - Gene ResultFOXM1 forkhead box M1 [ (human)]
FOXM1: a new therapeutic target of extramammary Paget disease. Epigenomic analyses identify FOXM1 as a key regulator of anti-tumor immune response in esophageal adenocarcinoma. FOXM1 Participates in Trophoblast Migration and Early Trophoblast Invasion: Potential Role in Blastocyst Implantation.
FOXM1: A key oncofoetal transcription factor in health and …
2014年12月1日 · Forkhead Box M1 (FOXM1) is a bona fide oncofoetal transcription factor, which orchestrates complex temporal and spatial gene expression throughout embryonic and foetal development as well as during adult tissue homeostasis and repair.
Targeting the oncogenic transcription factor FOXM1 to improve …
2023年6月27日 · We discuss new inhibitors of FOXM1 and highlight FOXM1 as an attractive target for controlling drug-resistant and difficult-to-suppress breast cancers, and how blocking FOXM1 might improve outcomes for patients with all subtypes of breast cancer.
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