Genotoxicity - Wikipedia
Genotoxicity is the property of chemical agents that damage the genetic information within a cell causing mutations, which may lead to cancer. While genotoxicity is often confused with mutagenicity, all mutagens are genotoxic, but some genotoxic substances are not mutagenic. The alteration can have direct or indirect effects on the DNA: the ...
遺傳毒性 - 维基百科，自由的百科全书
遺傳毒性或基因毒性（英語： Genotoxicity ）是指會破壞細胞內遺傳物質完整性的物理或化學因子 [1] ，如六價鉻、苯、芳香胺等突變原或致癌物質，游離輻射也具有基因毒性 [2] 。
Genotoxicity: damage to DNA and its consequences - PubMed
A genotoxin is a chemical or agent that can cause DNA or chromosomal damage. Such damage in a germ cell has the potential to cause a heritable altered trait (germline mutation). DNA damage in a somatic cell may result in a somatic mutation, which may lead to …
Genotoxicity is a word used in genetics that describes the possession of substance that has destructive effect on the genetic material of the cell (DNA, RNA) thus affecting the integrity of the cell. Genotoxins are mutagens that can cause genotoxicity leading to the damage of DNA or chromosomal material thus causing mutation.
基因毒性 - 百度百科
基因毒性（genotoxicity），是指污染物能直接或间接损伤细胞DNA，产生致突变和致癌作用的程度。 环境中某些污染物具有基因毒性，例如，多环芳烃中的苯并芘，可致突变.使原癌基因和肿瘤抑制基因发生改变。
遗传毒性研究（Genotoxicity Study）是药物非临床安全性评 价的重要内容，与其他研究尤其是致癌性、生殖毒性等研究有着 密切的联系，是药物进入临床试验及上市的重要环节。
Genotoxicity - an overview | ScienceDirect Topics
Genotoxicity is the ability of chemicals to damage the genetic information within a cell resulting in mutations, which may lead to malignancies. The genotoxic substances induce damage to the genetic material in the cells through interactions with the DNA sequence and structure.
The various aspects of genetic and epigenetic toxicology: testing ...
2017年5月22日 · In genetics, genotoxicity refers to the ability of harmful substances to damage genetic information. It is often confused with mutagenicity, which refers to the permanent transmissible variations in the amount and structure of genetic materials of cells or organisms that can increase the frequency of mutations.
Genotoxicity - an overview | ScienceDirect Topics
Genotoxicity refers to the ability of chemicals to damage DNA and/or cellular components regulating the fidelity of the genome – such as the spindle apparatus, topoisomerases, DNA repair systems and DNA polymerases – and includes all adverse effects on genetic information. These potentially harmful effects on genetic material may be ...
Genotoxicity: damage to DNA and its consequences
A genotoxin is a chemical or agent that can cause DNA or chromosomal damage. Such damage in a germ cell has the potential to cause a heritable altered trait (germline mutation). DNA damage in a somatic cell may result in a somatic mutation, which may lead to …
- 某些结果已被删除