Human Leukocyte Antigen B27 (HLA-B27) - Healthline
2018年11月13日 · An HLA-B27 test is a blood test that identifies HLA-B27 proteins. Human leukocyte antigens (HLAs) are proteins commonly found on white blood cells. These antigens help your immune system...
HLA-B27 - Wikipedia
Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) [1] is a class I surface molecule encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6 and presents antigenic peptides (derived from self and non-self antigens) to T cells.
I have a positive HLA-B27 what does it mean? - RheumDoctor
2018年6月5日 · HLA-B27 is a genetic test. The majority of people who have a positive HLA-B27 are perfectly healthy. HOWEVER, having a positive HLA-B7 can put you at increased risk of developing what we call spondyloarthritis-associated diseases. This is a …
HLA-B27 Syndromes - StatPearls - NCBI Bookshelf - National …
2023年7月4日 · Objectives: Identify the etiology of HLA-B27 associated medical conditions and emergencies. Review the evaluation of HLA-B27 associated syndromes. Summarize the treatment and management options available for HLA-B27 associated syndromes.
HLA-B27 antigen Information | Mount Sinai - New York
Learn about HLA-B27 antigen, find a doctor, complications, outcomes, recovery and follow-up care for HLA-B27 antigen.
HLA-B27 Gene and Arthritis - Arthritis Foundation
2022年6月24日 · HLA-B27 and Ankylosing Spondylitis. There are hundreds of HLA genes, each identified by a different number. One gene, HLA-B27, is strongly associated with a big family of rheumatic diseases called spondyloarthropathies. It includes: Axial spondyloarthritis; Axial psoriatic arthritis; Reactive arthritis
HLA-B27 Antigen - University of Rochester Medical Center
This test looks for HLA-B27, which are proteins called antigens. These are found on the surface of white blood cells that are fighting infection. If you have HLA-B27, you may have an autoimmune disease.
HLA-B27 Syndromes: Overview, Pathophysiology, Clinical ... - Medscape
2014年10月1日 · HLA-B27 associated AAU is the most frequent type of non-infectious uveitis (see Figure 1), accounting for 18-32% of cases in western countries and for 6-13% of cases in Asia. The relatively...
Autoinflammation and HLA-B27: More than an Antigen - PMC
The robust association with HLA-B27, an antigen presenting complex, is the strongest argument that adaptive immunity is important in these diseases. However, mounting evidence suggests that the role of HLA-B27 may not be so simple and that it …
HLA-B27: natural function and pathogenic role in spondyloarthritis
2002年5月9日 · The human leukocyte antigen HLA-B27 is strongly associated with development of a group of inflammatory arthritides collectively known as the spondyloarthritides. We have set out to define the natural immunological function of HLA-B27, and then to apply this knowledge to understand its pathogenic role.