Huntington's disease - Wikipedia
Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease [7] that is mostly inherited. [8] The earliest symptoms are often subtle problems with mood or mental/psychiatric abilities.
亨廷顿病 - 百度百科
亨廷顿病（Huntington's disease，缩写 HD），又称大舞蹈病或亨廷顿舞蹈症(Huntington's chorea)，是一种常染色体显性遗传性神经退行性疾病。 该病由美国医学家乔治亨廷顿于1872年发现，因而得名。
亨丁頓舞蹈症 - 维基百科，自由的百科全书
亨丁頓舞蹈症（Huntington's Disease, HD）是一種遺傳性疾病，會導致腦細胞死亡 [1] 。早期症狀往往是情緒或智力方面的輕微問題 [2] ，接著是不協調和不穩定的步態 [3] 。
Huntington's disease - Symptoms and causes - Mayo Clinic
2024年4月25日 · The movement disorders related to Huntington's disease may cause movements that can't be controlled, called chorea. Chorea are involuntary movements affecting all the muscles of the body, specifically the arms and legs, the face and the tongue.
Chorea: What It Is, Causes, Treatment & Risk Factors - Cleveland Clinic
Overactivity of a hormone called dopamine in the part of your brain that affects your movement (basal ganglia) causes chorea. The most common causes of chorea include: An underlying genetic condition like Huntington’s disease. A movement disorder like Parkinson’s disease or tardive dyskinesia.
Chorea & Huntington's Disease - The Movement Disorder Society
Chorea is an abnormal involuntary movement derived from the Greek word “dance”. It is characterized by brief, abrupt, irregular, unpredictable, non-stereotyped movements. In milder cases, chorea may appear purposeful.
Huntington's Disease | National Institute of Neurological …
2024年7月19日 · People living with HD develop uncontrollable dance-like movements (chorea) and abnormal body postures, as well as problems with behavior, emotion, thinking, and personality. For example, uncontrolled movements in the person's fingers, feet, face, or torso. These movements are signs of chorea.
Chorea: A Journey through History - PMC - National Center for ...
2015年5月28日 · Huntington viewed chorea as a spectrum extending from childhood to adulthood although related to distinct causes (SC and HD). 65 Osler, writing his “On chorea and choreiform affectations” (1894), settled this distinction and expanded the clinical and pathological studies of chorea based on his extensive patient population, mostly children ...
Therapy development in Huntington disease: From current …
This appearance of rhythmic uncontrolled movements led clinicians to describe the disorder as Huntington chorea to emphasize the “dance-like” appearance of these movements. With progression of the involuntary movement disorder, the clinical course is then characterized by cognitive decline, exhibited by an inability to perform sequenced ...
Huntington Disease - GeneReviews® - NCBI Bookshelf
1998年10月23日 · Chorea, an involuntary movement disorder consisting of nonrepetitive, nonperiodic jerking of limbs, face, or trunk, is the major sign of the disease. Chorea is present in more than 90% of individuals, and typically increases in severity during the first ten years.