8-Hydroxyquinoline - Wikipedia
8-Hydroxyquinoline (also known as oxine) is an organic compound derived from the heterocycle quinoline. A colorless solid, its conjugate base is a chelating agent, which is used for the quantitative determination of metal ions.
8-羟基喹啉 - 百度百科
8-羟基喹啉，是一种有机化合物，化学式为C9H7NO，为白色或淡黄色结晶性粉末，不溶于水、乙醚，溶于乙醇、丙酮、氯仿、苯、无机酸，主要用作医药、染料、农药的中间体，也可用作沉淀和分离金属离子的络合剂和萃取剂。 2017年10月27日， 世界卫生组织 国际癌症研究机构 公布的 致癌物 清单初步整理参考，8-羟基喹啉在 3类致癌物 清单中。 [1] 小鼠皮下LCLo：83600 μg/kg。 大鼠：＞1210 mg/m 3 /6h。 [2] 主要用作医药、染料、农药的中间体，也可用作沉淀和分离金属 …
Insights of 8-hydroxyquinolines: A novel target in medicinal chemistry
2021年3月1日 · 8-Hydroxyquinoline (8-HQ) is a significant heterocyclic scaffold in organic and analytical chemistry because of the properties of chromophore and is used to detect various metal ions and anions. But from the last 2 decades, this moiety has been drawn great attention of medicinal chemists due to its significant biological activities.
Hydroxyquinoline - an overview | ScienceDirect Topics
Hydroxyquinoline is a heterocyclic scaffold that is widely used in organic and analytical chemistry. It is known for its properties of chromophore and metal chelation, making it useful for detecting metal ions and anions, as well as for developing potent drug molecules for the treatment of various diseases.
Recent Advances in the Synthesis and Biological Activity of 8 ...
2020年9月21日 · The 8-hydroxyquinoline moiety can act as a building block for various pharmacologically active scaffolds. In the present work, we have reviewed the recent literature pertaining to the synthesis and bioactivity of numerous 8-HQ derivatives as anticancer, antiviral, antimicrobial, antibacterial, antifungal, and anticancer agents.
8-Hydroxyquinolines: a review of their metal chelating properties …
Metal imbalance is the leading cause for many neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. 8-Hydroxyquinoline (8HQ) is a small planar molecule with a lipophilic effect and a metal chelating ability.
Oxyquinoline | C9H7NO | CID 1923 - PubChem
Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products. View More... See also: Acetic acid; …
Quinolones | C9H7NO | CID 6038 - PubChem
Quinolin-2-ol is a monohydroxyquinoline carrying a hydroxy substituent at position 2. It is an intermediate metabolite produced duting the microbial degradation of quinoline. It has a role as a bacterial xenobiotic metabolite. It is a tautomer of a quinolin-2 (1H)-one.
(PDF) 8-Hydroxyquinolines: A review of their metal ... - ResearchGate
2013年10月3日 · Herein, diverse bioactivities of 8HQ and newly synthesized 8HQ-based compounds are discussed together with their mechanisms of actions and structure-activity relationships. Structure of...
8-Hydroxyquinoline: a privileged structure with a broad-ranging ...
Among the quinoline core compounds, the most frequently encountered in medicinal chemistry is 8-hydroxyquinoline (8-HQ), which is one of the most important strong metal ion chelator groups and represents an excellent scaffold with a wide spectrum of pharmacological applications such as iron-chelators for neuroprotection, anticancer agents ...