Engineered E. coli Shrink Tumors in Mice - NCI - National Cancer …
2024年12月11日 · Researchers have engineered a strain of the bacteria E. coli, called Nissle 1917, in two different ways to be forms of immunotherapy. Both approaches shrank tumors in mice.
Immunotherapy for Cancer - NCI
2019年9月24日 · Immunotherapy helps the immune system to better act against cancer. What are the types of immunotherapy? Several types of immunotherapy are used to treat cancer.
Study of Sacituzumab Govitecan Versus Treatment of Physician's …
The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer who have received prior treatment with platinum-based chemotherapy and immunotherapy, versus the treatment of physician's choice (TPC).
Progress against RAS-driven cancers lauded at RAS Symposium, …
2024年12月16日 · One promising approach is to combine KRAS inhibitors with other types of cancer treatments, including chemotherapy, immunotherapy, and PARP inhibitors. Presenters cited preclinical models of pancreatic cancer treated with an EGFR inhibitor and a KRAS inhibitor that showed tumor regression, as did another model treated with three drugs.
DR-18 for the Treatment of Relapsed or Persistent Acute Myeloid ...
I. Evaluate the feasibility and safety of 4-week administration of DR-18 induction immunotherapy to adults with recurrent AML/MDS after allogeneic HCT. II. Identify the maximum tolerated dose (MTD).
Immune Checkpoint Inhibitors - NCI - National Cancer Institute
Immunotherapy drugs called immune checkpoint inhibitors work by blocking checkpoint proteins from binding with their partner proteins. This prevents the “off” signal from being sent, allowing the T cells to kill cancer cells. One such drug acts against a checkpoint protein called CTLA-4.
Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post ...
Researchers are looking for new ways to treat people with endometrial cancer (EC) who have previously received treatment with platinum based therapy (a type of chemotherapy) and immunotherapy. Immunotherapy is a treatment that helps the immune system fight cancer.
Side Effects of Immunotherapy - NCI - National Cancer Institute
Immunotherapy side effects happen when the immune system that has been prompted to act against the cancer also acts against healthy cells and tissues in the body. Learn about the types of side effects that immunotherapy might cause and where to go for more information.
A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced …
Any standard cancer therapy (eg, chemotherapy, hormonal therapy, radiotherapy, immunotherapy, biologic therapy treatment) or experimental therapy within 3 weeks or 5 half-lives, whichever is shorter, prior to C1D1.
Targeted Photoimmunotherapy for Cancer - NCI - National Cancer …
2016年4月25日 · Two new studies from NCI researchers add to growing evidence of the promise of a novel type of cancer immunotherapy that uses infrared light to activate rapid and selective killing of cancer cells.