Kidney Hypertrophy - an overview | ScienceDirect Topics
Kidney hypertrophy is the earliest structural change in type 1 diabetes but is not reflected in any specific light microscopic changes. In many patients, glomerular structure remains normal or …
Kidney Hypertrophy - an overview | ScienceDirect Topics
Kidney hypertrophy refers to the enlargement of kidney cells, particularly observed in conditions such as compensatory renal growth, chronic metabolic acidosis, and diabetes mellitus. It can …
Kidney atrophy vs hypertrophy in diabetes: which cells are …
One of the first structural changes in diabetic nephropathy (DN) is the renal enlargement. These changes resulted in renal hypertrophy in both glomerular and tubular cells. Shrink in the kidney …
Kidney Hypertrophy - an overview | ScienceDirect Topics
The kidney adapts to altered demands by functional and structural changes. Compensatory hypertrophy occurs in the kidney after extirpation of the contralateral kidney. Hypertrophy is …
Hypertrophy and hyperfunction of the diabetic kidney - PMC
Diabetes is the leading cause of chronic renal failure. However, in the early phase of diabetes, before complications have set in, the glomerular filtration rate (GFR) is elevated in a …
Glomerular hyperfiltration and hypertrophy: an evaluation of …
Sustained glomerular hyperfiltration and hypertrophy can lead to glomerular injury and progressive kidney damage. This article explores the relationship between obesity and chronic …
Renal hypertrophy, growth factors, and nephropathy in …
In early type 1 diabetes mellitus, hypertrophy of the kidney is a consistent finding. It is easily diagnosed using current noninvasive methods, especially ultrasonography. Renal functional …
Signaling mechanisms in renal compensatory hypertrophy
2023年6月16日 · Here, we use a multi-omic approach in a unilateral nephrectomy model in male mice to identify signaling processes associated with renal compensatory hypertrophy, …
Molecular mechanisms of renal hypertrophy: Role of p27Kip1 - Kidney …
Molecular mechanisms of renal hypertrophy: Role of p27 Kip1. There are two fundamentally different growth responses for cells comprising the nephron: hyperplasia or hypertrophy. Cells …
Kidney growth and hypertrophy: the role of mTOR and vesicle …
2015年6月1日 · It is the nephron that is the organ, and in vertebrates, all these units are packaged in one place — the kidney. Removal of one kidney causes a compensatory hypertrophy of the …