List of Macrolides - Drugs.com
Macrolides are a class of antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), a type of soil-borne bacteria. Macrolides inhibit protein synthesis in bacteria by reversibly binding to the P site of the 50S unit of the ribosome.
Macrolide - Wikipedia
Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14-, 15-, or 16-membered. Macrolides belong …
Macrolides: Drug Class, Uses, Side Effects, Drug Names - RxList
Macrolides are antibiotics used for infections caused by gram-positive bacteria (streptococcal and pneumococcal infections). Learn about how they work, usages, side effects, and a list of drugs.
Macrolides - StatPearls - NCBI Bookshelf
2020年2月1日 · Macrolides are a class of drugs used to manage and treat various bacterial infections. Azithromycin, clarithromycin, and erythromycin are commonly used to treat infections like pneumonia, sinusitis, pharyngitis, and tonsillitis. They are also used in uncomplicated skin infections and otitis media in pediatric patients.
大环内酯类抗生素 - 百度百科
大环内酯类抗生素（macrolides antibiotics，MA）是一类分子结构中具有12-16 碳内酯环的抗菌药物的总称，通过阻断50s 核糖体中肽酰转移酶的活性来抑制细菌蛋白质合成，属于快速抑菌剂。
大環內酯 - 维基百科，自由的百科全书
大環內酯（ macrolides ），或稱巨環內酯，是一組其作用在於結構內的「大環」的藥物（一般都是抗生素），這個大環亦即是一連結一個或多個脫氧糖（多是红霉糖及 去氧糖胺 （ 英语 ： desosamine ） ）的內酯環。內酯環可以是由14、15或16個單元組成。
大环内酯（Macrolides）类抗生素药物综述 - 知乎
2023年11月28日 · 抗菌药物（antibacterial drugs）来源于细菌、霉菌，或者通过化学的从头合成（de novo synthesis）制备。 从技术上讲，“抗生素（antibiotics）”仅指那些源自细菌或霉菌的抗菌剂，但通常与“抗菌药物（antibacterial drugs，或antibacterials）”同义使用。 抗生素有许多作用机制，包括：抑制细胞壁合成、增加细胞膜通透性、干扰蛋白质合成、核酸代谢和其他代谢过程（如叶酸合成）（图1）。 图1. 抗生素常见的作用机制。 许多抗生素在化学上是相关的，因此可 …
PharmGKB summary: macrolide antibiotic pathway, …
Macrolides are a class of broad spectrum antibiotics of large molecular size. The class includes erythromycin, clarithromycin, and azithromycin, among others [1]. Macrolides are used to treat both local and systemic infections, including infections of the skin, respiratory tract, gastrointestinal tract, and genital tract [2].
大环内酯（Macrolides）类抗生素药物综述 - 推荐阅读
2023年2月22日 · 抗菌药物（antibacterial drugs）来源于细菌、霉菌，或者通过化学的从头合成（de novo synthesis）制备。 从技术上讲，“抗生素（antibiotics）”仅指那些源自细菌或霉菌的抗菌剂，但通常与“抗菌药物（antibacterial drugs，或antibacterials）”同义使用。 抗生素或抗菌药物. 抗菌药物（antibacterial drugs）来源于细菌、霉菌，或者通过化学的从头合成（de novo synthesis）制备。 从技术上讲，“抗生素（antibiotics）”仅指那些源自细菌或霉菌的抗菌剂， …
Macrolides: Classification, Dose, Indications, and Contraindications
2023年12月30日 · Macrolides are a class of antibiotics characterized by a distinctive macrocyclic lactone ring structure. These antibiotics are effective against a wide range of bacteria, particularly Gram-positive bacteria. The mechanism of action of macrolides involves inhibiting bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit.