Motilin - Wikipedia
The main function of motilin is to increase the migrating myoelectric complex component of gastrointestinal motility and stimulate the production of pepsin. Motilin is also called "housekeeper of the gut" because it improves peristalsis in the small intestine and clears out the gut to prepare for the next meal. [9]
Physiology, Motilin - StatPearls - NCBI Bookshelf
2022年9月26日 · Motilin is the hormone that is cyclically released during the fasted state and is released by the entero-endocrine cells (Mo cells) in the upper small intestine. Motilin stimulates gastric and small intestine motility, causing undigested food in …
Motilin Hormone: Function and What it Is - Cleveland Clinic
2022年5月16日 · Motilin is a hormone that stimulates your digestive system. It helps move food from your small intestine to your large intestine. Motilin also plays a role in controlling insulin release and triggering hunger cues. If you have low motilin, you may have slow or delayed muscle contractions in your small intestine.
Motilin Receptor Agonist - an overview | ScienceDirect Topics
Motilin is a 22-amino-acid peptide, secreted from EC cells, that stimulates gut motility through activation of a G-protein–coupled motilin receptor found in the enteric nervous system and intestinal smooth muscle. 45 Recently a nonantibiotic, orally active motilin agonist, Mitemcinal, has been developed and is in phase 2 trials for IBS and ...
What Is Motilin? Function & Role in Gut Health - SelfHacked
2019年12月16日 · Motilin is a hormone produced by cells in the small intestine. Its name comes from its ability to stimulate the movement (motility) of the digestive organs. Its main function is to cause movement and emptying of the digestive tract …
Ghrelin and motilin receptors as drug targets for ... - Nature
2015年9月22日 · Thus, the most promising uses of motilin receptor agonists are the treatment of gastroparesis or conditions with slow gastric emptying, and ghrelin receptor agonists hold potential for the...
Motilin - an overview | ScienceDirect Topics
Motilin is a 22-amino-acid peptide, secreted from EC cells, that stimulates gut motility through activation of a G-protein–coupled motilin receptor found in the enteric nervous system and intestinal smooth muscle. From: Gastroenterology Clinics of North America, 2010
Physiological functions and potential clinical applications of motilin ...
2023年2月1日 · Motilin is a gastrointestinal hormone secreted by the duodenum. This peptide regulates a characteristic gastrointestinal contraction pattern, called the migrating motor complex, during the fasting state. Motilin also affects the pressure of the lower esophageal sphincter, gastric motility and gastric accommodation in the gastrointestinal tract.
Motilin - PubMed
Motilin is a fascinating hormone for the physiologist. Its interaction with the family member ghrelin and with obestatin will open new areas for basic research. Motilin-receptor agonists or antagonists could soon be part of the therapeutic arsenal of the clinician to improve digestive dysmotility.
Motilin Comparative Study: Structure, Distribution, Receptors, and ...
Motilin, produced in endocrine cells in the mucosa of the upper intestine, is an important regulator of gastrointestinal (GI) motility and mediates the phase III of interdigestive migrating motor complex (MMC) in the stomach of humans, dogs and house musk shrews through the specific motilin receptor (MLN-R).
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