mTOR - Wikipedia
mTOR signaling intersects with Alzheimer's disease (AD) pathology in several aspects, suggesting its potential role as a contributor to disease progression. In general, findings demonstrate mTOR signaling hyperactivity in AD brains.
mTOR 通路 | Cell Signaling Technology
Discover the mTOR pathway and its role in cellular growth and metabolism. Click here to explore the intricacies of this vital signaling pathway.
mTOR Signaling in Growth, Metabolism, and Disease - PMC
Extensive research over the past two decades has established a central role for mTOR in regulating many fundamental cell processes, from protein synthesis to autophagy, and deregulated mTOR signaling is implicated in the progression of cancer and diabetes, as well as the aging process.
综述浅读| mTOR到底是个啥 - 知乎 - 知乎专栏
哺乳动物雷帕霉素靶蛋白(mammalian target of rapamycin, mTOR)是一种非典型丝氨酸/苏氨酸蛋白激酶，为磷脂酰肌醇激酶相关激酶(phosphatidy-linositol kinase-related kinase, PIKK)蛋白质家族成员。
mTOR Pathway - Cell Signaling Technology
Discover the mTOR pathway and its role in cellular growth and metabolism. Click here to explore the intricacies of this vital signaling pathway.
mTOR Signaling in Growth, Metabolism, and Disease - Cell Press
Here, we review recent advances in our understanding of mTOR function, regulation, and importance in mammalian physiology. We also highlight how the mTOR signaling network contributes to human disease and discuss the current and future prospects for therapeutically targeting mTOR in the clinic.
mTOR signaling at a glance - PMC - PubMed Central (PMC)
The mammalian target of rapamycin (mTOR) signaling pathway integrates both intracellular and extracellular signals and serves as a central regulator of cell metabolism, growth, proliferation and survival.
Multifaceted role of mTOR (mammalian target of rapamycin) signaling …
2023年10月2日 · The mTOR signaling cascades control the cellular growth and mitotic divisions by generating prominent metabolic energy from glucose, lipid, protein, and nucleotides while inhibiting catabolic ...
Extensive research over the past two decades has established a central role for mTOR in regulating many fundamental cell pro-cesses, from protein synthesis to autophagy, and deregulated mTOR signaling is implicated in the progression of cancer and diabetes, as well as the aging process.
mTOR Signaling in Growth Control and Disease - Cell Press
The mechanistic target of rapamycin (mTOR) signaling pathway senses and integrates a variety of environmental cues to regulate organismal growth and homeostasis. The pathway regulates many major cellular processes and is implicated in an increasing number of pathological conditions, including cancer, obesity, type 2 diabetes, and neurodegeneration.