核因子 kappa B 亚基 1（NFKB1）基因 | MCE - MCE-生物活性 ...
NFKB 是一种转录调节因子，可被各种细胞内和细胞外刺激激活，例如细胞因子、氧化自由基、紫外线照射以及细菌或病毒产物。 激活的 NFKB 转移到细胞核中并刺激参与多种生物功能的基 …
The wild-type (WT), H67R, and I553M mutant NFKB1 full-length cod-ing sequences were commercially cloned into a Gateway-compatible entry-vector (GenScript, Piscataway, NJ). …
Late-Onset Antibody Deficiency Due to Monoallelic Alterations in NFKB1
Nov 13, 2019 · We detected two single base pair deletions and two single base pair insertions, causing severe protein truncations, and one missense mutation. Immunoblotting, lymphocyte …
UniProt
Jun 20, 2002 · The NF-kappa-B p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3. NFKB1 appears to have dual functions …
Molecular docking analysis of nuclear factor-κB and genistein ...
Targeting NF-κB activity inhibition may serve as a novel approach through which, genistein suppresses the breast cancer growth and progression. The sequence, structure and functional …
NFKB1 Gene - GeneCards | NFKB1 Protein | NFKB1 Antibody
Dec 25, 2024 · NFKB1 (Nuclear Factor Kappa B Subunit 1) is a Protein Coding gene. Diseases associated with NFKB1 include Immunodeficiency, Common Variable, 12, With Autoimmunity …
NFKB1: a suppressor of inflammation, ageing and cancer
Here we discuss recent results that reveal that the nuclear factor of kappa light polypeptide gene enhancer in B‐cells 1 (NFKB1) (p105/p50) subunit is an important regulator of NF‐κB activity in …
Nuclear factor-κB1: Regulation and function - ScienceDirect
Jan 1, 2008 · NF-κB (NF-κB) is a pleiotropic transcription factor regulating over 200 genes involved in cell function and inflammation. The Rel or NF-κB family is comprised of hetero- or …
NFKB1 nuclear factor kappa B subunit 1 [ (human)] - National …
High NFKB1 expression is associated with inflammatory uveal melanoma. NFKB1 rs28362491 polymorphism was significantly associated with the risk of head and neck carcinoma, …
NFKB1 - Wikipedia
NF-κB is a transcription factor that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products.