Neuroprotection - Wikipedia
Lithium exerts neuroprotective effects and stimulates neurogenesis via multiple signaling pathways; it inhibits glycogen synthase kinase-3 (GSK-3), upregulates neurotrophins and growth factors (e.g., brain-derived neurotrophic factor (BDNF)), modulates inflammatory molecules, upregulates neuroprotective factors (e.g., B-cell lymphoma-2 (Bcl-2 ...
Neuroprotection - an overview | ScienceDirect Topics
This chapter presents an overview on neuroprotective natural products, predominantly from plant origins, their plausible mechanisms of actions, and in silico approaches to identify natural products leads with potential neuroprotective and therapeutic applications in CNS disorders.
Neuroprotection - an overview | ScienceDirect Topics
The neuroprotective and inhibitory actions of anti-angiogenic, anti-inflammatory agents and free radical scavengers against neurodegeneration process are well understood [271,272]. In the pathogenesis of neurodegenerative conditions, neuroinflammation may drive the progression of the disease to a chronic condition as the result of production of ...
Neuroprotection in acute brain injury: an up-to-date review
2015年12月1日 · In this paper, we summarize the current status in terms of neuroprotective strategies, both in the immediate and later stages of acute brain injury in adults. We also review potential new strategies and highlight areas for future research.
Neuroprotection strategies in traumatic brain injury: Studying the ...
It is crucial to comprehend how different neuroprotective methods and treatments can be effective in reducing the impact of TBI and enhancing patient outcomes. This review intends to cover a broad spectrum of neuroprotective approaches, encompassing pharmaceutical treatments, natural compounds, as well as cellular and molecular methods.
Mechanisms and Potential Benefits of Neuroprotective Agents in …
2024年12月18日 · Most agents can cross the blood–brain barrier (BBB) and reach individual neurons. Neuroprotective agents are used to protect neuronal structure and function and reverse or prevent some of the damage by reducing or stopping neuron loss .
Neuroprotective Strategies for Neurological Disorders by …
Due to the scarcity of human studies on neuroprotective effects of natural products, this review focuses on the various established activities of natural products in in vitro and in vivo preclinical models, and their potential neuro-therapeutic applications using the …
Neuroprotection: Strategies and Practices for Optimal Brain Health
Neuroprotective agents work by targeting specific cellular processes and mechanisms involved in neuronal damage, such as inhibiting the release of excitotoxic neurotransmitters, reducing the production of harmful free radicals, and suppressing inflammation.
Neuroprotection: Method and Protocols | SpringerLink
This volume contains cutting-edge molecular biology methods on neuroprotective mechanisms and specific preclinical models of the CNS injury, iseases and planning translation.
Emerging Neuroprotective Strategies for the Treatment of …
The neuroprotective function of vinpocetine has been attributed to multiple mechanisms of action (Zhang et al., 2018). In the brain, vinpocetine improves blood flow through its inhibition of phosphodiesterase 1 (PDE1) that catalyzes the degradation of cAMP and cGMP, two known vasodilators ( Al-Kuraishy et al., 2020 ; Medina, 2011 ; Paterno et ...