Sickle Cell Disease - Causes and Risk Factors - NHLBI, NIH
2024年8月20日 · This child does not have sickle cell trait or disease. A 50%, or 1 in 2, chance of inheriting one normal hemoglobin A gene and one hemoglobin S gene. This child has sickle cell trait and is a carrier of the hemoglobin S gene. A 25%, or 1 in 4, chance of inheriting two hemoglobin S genes. This child has sickle cell disease.
Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH
2024年9月30日 · Sickle cell disease affects more than 100,000 people in the United States and 8 million people worldwide. In the United States, 9 of 10 people who have sickle cell disease are of African ancestry or identify as Black: About 1 in 13 Black babies are born with sickle cell trait, meaning that they inherited a sickle cell gene from one parent.
Sickle Cell Disease - Sickle Cell Trait - NHLBI, NIH
2024年8月22日 · Sickle cell trait occurs when a person has one copy of the sickle cell gene passed down from one parent along with a normal hemoglobin gene (hemoglobin A) from the other parent. People who have sickle cell trait are sometimes called carriers . Sickle cell trait is different from sickle cell anemia or sickle cell disease.
Sickle Cell Disease - Treatment - NHLBI, NIH
2024年9月30日 · Hydroxyurea is an oral medicine that is frequently prescribed to help treat sickle cell disease. Hydroxyurea is an oral medicine that can reduce sickling of red blood cells and help prevent serious symptoms of sickle cell disease, including pain crises. Healthcare providers usually prescribe daily hydroxyurea for infants as young as 9 months ...
Sickle Cell Disease - Symptoms - NHLBI, NIH
2024年8月20日 · Serious symptoms of sickle cell disease are emergencies and need treatment right away. Seek care or call 9-1-1 if you or someone else is experiencing: Severe pain. A serious pain event is sometimes called a “pain crisis,” “sickle cell crisis,” or “vaso-occlusive crisis.” Most people with sickle cell disease have this often-serious pain.
SICKLE CELL DISEASE Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. People with SCD are born with it. This disease gets its name from the abnormal crescent or “sickle” shape that some red blood cells develop. Because of this shape and other abnormalities, sickled
Sickle Cell Disease - Diagnosis - NHLBI, NIH
2024年9月9日 · Newborn screening programs also find out whether your baby has sickle cell trait and is a carrier of the hemoglobin S gene. If this is the case, genetic counseling will be offered. Remember that when a child has sickle cell trait or sickle cell disease, their future siblings or your child’s future children may be a carrier of the hemoglobin S ...
Sickle Cell Disease Research - NHLBI, NIH
2024年8月23日 · The National Institutes of Health (NIH) has supported research on sickle cell disease — also called sickle cell anemia — since before the NHLBI’s founding in 1948. With each passing decade, the NHLBI has kept a focus on advancing the understanding of sickle cell disease and improving clinical care for people who have it.
A Collaborative Patient-Focused Approach to Cure Sickle Cell …
2018年9月17日 · This patient-focused initiative builds on the legacy of NHLBI-supported research that has contributed to improving clinical care for patients who have sickle cell disease. It also complements the institute’s broader sickle cell disease research investment, which includes basic, clinical, translational and implementation science research.
Study identifies genetic factors that may explain long ... - NHLBI, NIH
2020年8月12日 · To find out, the researchers conducted genetic sequencing among 192 people with sickle cell anemia in sub-Saharan Africa, specifically Cameroon. They further divided the group into long-term survivors over 40 years, a “stroke” group (at least one episode of stroke), and a “random” group of patients younger than 40 years without stroke.