Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH
2024年9月30日 · Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood cells are disc-shaped and flexible so they can move easily through the blood vessels. In sickle cell disease, red blood cells are misshaped, typically ...
Sickle Cell Disease - Causes and Risk Factors | NHLBI, NIH
2024年8月20日 · However, in sickle cell disease, the body has trouble keeping up with the rate that the cells are being destroyed. This can lead to a low number of red blood cells, called anemia. The resulting anemia can cause a person to be easily tired with less energy. Normal red cells and sickled red cells.
Sickle Cell Disease - Treatment | NHLBI, NIH
2024年9月30日 · How Sickle Cell Disease May Affect Your Health. Last updated on September 30, 2024. Treatment options for sickle cell disease include medicines that lessen symptoms, blood transfusions, blood and bone marrow transplants, and gene therapy treatments. Bone marrow transplants and gene therapies are potential cures for some people.
Hydroxyurea Use for Sickle Cell Disease Fact Sheet
Hydroxyurea is an oral medicine that can help reduce sickle cell disease complications. This fact sheet will provide the facts about hydroxyurea, potential benefits and risks, and questions to ask your healthcare provider. Print Length:
Sickle Cell Disease: Milestones in Research and Clinical Progress ...
Overview. Learn about the history of sickle cell disease in the United States, from its discovery in 1910 to the NHLBI legacy of research that has advanced the understanding of sickle cell disease, improved clinical progress, and paved the way for widely available cures. Print Length:
Sickle Cell Disease Research | NHLBI, NIH
2024年8月23日 · The National Institutes of Health (NIH) has supported research on sickle cell disease — also called sickle cell anemia — since before the NHLBI’s founding in 1948. With each passing decade, the NHLBI has kept a focus on advancing the understanding of sickle cell disease and improving clinical care for people who have it.
Sickle Cell Disease: Research, Programs, and Progress
Cure Sickle Cell Initiative. A national health education program that aims to bring greater visibility to blood diseases and disorders like anemia, sickle cell disease and others, their diagnosis, treatment and management, and blood safety by translating research for patients and professionals. The NHLBI is a global leader in blood-related ...
Cure Sickle Cell Initiative - NHLBI, NIH
The Cure Sickle Cell Initiative is an NHLBI-led collaborative research effort that is accelerating the development of gene therapies to cure sickle cell disease. The Initiative identifies and supports promising gene therapies that are currently being tested in multicenter clinical research trials. One of these studies is co-funded by the ...
How Sickle Cell Disease May Affect Your Health - NHLBI, NIH
2024年8月22日 · It filters your blood and destroys old blood cells. In people who have sickle cell disease, red blood cells may get trapped in the spleen. This makes the spleen quickly grow larger than normal. Serious anemia can occur when red blood cells get trapped in the spleen. A large spleen may also cause pain in the left side of the belly.
Sickle Cell Disease - Symptoms | NHLBI, NIH
2024年8月20日 · Serious pain linked with sickle cell disease often requires treatment in a clinic or hospital. Fatigue (extreme tiredness), shortness of breath, dizziness, and irregular heartbeat. These are symptoms of serious anemia. Life-threatening anemia can be caused by conditions such as a splenic sequestration crisis crisis or an aplastic crisis .