[G-CSF and Its Receptor in Hematonosis] - PubMed
Recently, CSF3R mutations have been discovered frequently in chronic neutrophilic leukemia (CNL). Such findings might provide the theoretical basis for the targeted therapy. In this review, the clinical application of G-CSF receptor in hematonosis is briefhy summarized.
Hematopoiesis - PMC
Hematopoiesis – the formation of blood cellular components – occurs during embryonic development and throughout adulthood to produce and replenish the blood system. Studying hematopoiesis can help scientists and clinicians to understand better the processes behind blood disorders and cancers.
Simultaneously multi-parameter determination of hematonosis …
In this paper, we report a cell-saving imaging method for quick identification of the hematonosis cell apoptosis induced by chemotherapeutic drugs.
Combined emapalumab and ruxolitinib in patients with …
Haemophagocytic lymphohistiocytosis (HLH) is a life-threatening systemic inflammatory disorder characterized by excessive activation of cytotoxic T cells and macrophages [1, 2]. Cytokines play a pivotal role in the progression of HLH and are thus mainly targeted in immunotherapy. IFN-γ is considered the most crucial cytokine in HLH pathology.
[G-CSF and Its Receptor in Hematonosis] - ResearchGate
2015年6月1日 · G-CSF acts by binding to its receptor G-CSFR (also called CSF3R), a member of the cytokine receptor type I superfamily, which after binding with G-CSF activates the canonical Janus kinase...
Haematopoiesis - Wikipedia
Haematopoiesis (/ hɪˌmætəpɔɪˈiːsɪs, ˌhiːmətoʊ -, ˌhɛmə -/; [1][2] from Ancient Greek αἷμα (haîma) 'blood' and ποιεῖν (poieîn) 'to make'; also hematopoiesis in American English, sometimes h (a)emopoiesis) is the formation of blood cellular components. All cellular blood components are derived from haematopoietic stem cells. [3] .
Myelodysplastic Syndrome Associated Hemophagocytic …
2023年11月2日 · Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder characterized by excessive cytokine secretion, resulting in hyperinflammation and multiorgan dysfunction. It is classified into primary HLH, which is mainly caused by genetic defects, and secondary HLH, triggered by various underlying conditions.
[Clinical Observation of Neutropenia Patients with Hematonosis …
Objective: To observe the clinical efficacy and safety of polymyxin B sulfate in febrile neutropenia patients with hematonosis. Methods: Clinical data of 50 patients in the department of hematology, Fujian Medical University Union Hospital from October 2019 to September 2020 were collected.
血液病分子库 | TargetMol - 上海陶术
血液病亦称为造血系统疾病，包括原发于造血系统疾病（如白血病原发于骨髓组织等）和主要累及造血系统疾病（如缺铁性贫血），例如白血病，血友病、再障、地中海贫血、骨髓增生异常综合症（MDS）、多发性骨髓瘤、淋巴瘤等。 血液系统疾病多半是难治性疾病， 发病隐袭，病状隐匿。 由于缺乏特效疗法，许多疾病曾被称为“不治之症”，近年来，随着医学研究的深入发展，血液病的治疗效果有了明显提高。 现代医学对血液病的治疗多应用激素、化疗等方法，但副作用大， …
Clinical significance of phenotypic features of blasts in patients …
2002年12月1日 · Myelodysplastic syndrome (MDS) is a malignant disorder of hematopoietic progenitors in which the bone marrow (BM) is composed of clonal hematopoietic cells showing various degrees of differentiation in each case. 1-3 The French-American-British (FAB) cooperative group proposed 5 subgroups of MDS based mainly on the percentage of …
- 某些结果已被删除