Opioids How much Loperamide... - Bluelight.org
2007年5月17日 · Loperamide is slow to take effect (and slow to metabolize, people get in trouble with doing every day because its absolute floor half life of 11h-- possibly much higher for larger doses-- means constantly escalating levels).
Regular recreational use of loperamide. - Bluelight.org
2011年5月16日 · I dose 100mg of loperamide, 50 2mg tablets, along with 2-3 tablespoons of black pepper and 25mg benadryl. The black pepper has piperine which supposedly helps it cross the BBB, and the benadryl is necessary because without it I become very nauseous and itchy.
Opioids - Loperamide (Imodium) Megathread v. 2 | Bluelight.org
2004年2月3日 · Loperamide is an opioid drug used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.In most countries it is available generically and under brand names such as Lopex, Imodium, Dimor, Fortasec, Lopedium, Gastro-Stop and Pepto Diarrhea Control.
Getting loperamide across the blood-brain barrier - Bluelight.org
2004年12月29日 · antagonist, against loperamide in the guinea pig ileum was 3.83 nM, and in the mouse vas deferens was 82.87 nM indicating that loperamide in the guinea pig ileum acts on mu receptors while in the mouse vas deferens on another opiate receptor. PMID: 6319884, UI: 84116593 morpheus (Hive Bee) 08-29-02 02:50 No 350368 Not shit Bookmark
(Loperamide/96 mgs) Experienced: YES, I'm high. - Bluelight.org
2003年11月4日 · Loperamide is much more dangerous than other opiates in high dosages, because unlike other opiates which are non-toxic, whose risk lies in overdosing, loperamide is quite toxic. If you read through this entire thread you will see various people posting about nearly dying or even having loved ones die from prolonged loperamide user.
How I kicked opiates by using loperamide - my story.
2003年11月4日 · But seriously, loperamide can fuck up your heart if you take to much, which it sounds like you did (for years). Severe cardiac arrhythmias including QTc prolongation can happen when you overtake loperamide. Today, loperamide holds a Black Box Warning for reports of Torsades de Pointes and sudden death when used in higher than recommended doses.
Opioids - Loperamide--->Suboxone. How to? - Bluelight.org
2019年3月19日 · It would be a really great resource if it weren't for the drug's potentially dangerous effects upon the heart. There are other Opioids, like Methadone for instance, that also effect the heart's QT interval. This can and has lead to documented cases of death resulting. So, Loperamide maintenance is not something we can condone.
Opioids - IV / injecting Loperamide | Page 2 | Bluelight.org
2014年4月7日 · ^ Yeah it is but the central effects of high-dose loperamide are well established. The science is simple - low doses do not produce central effects because a negligible amount remains in the brain due to P-gp but with sufficiently large doses, enough remains to produce significant central opioid effects.
Opioids - IV Loperamide experiment [Experience incoming over …
2010年1月14日 · Plus loperamide can cause in the worst case lethal heart problems (I know that methadone can prolong the Q/T interval too, but my point is, it's just dangerous) My point is, it's just to dangerous to fuck with and the reward is negligible.
One more word about getting high with loperamide (Immodium)
2003年11月4日 · When loperamide is taken by itself, it cannot readily cross the blood-brain barrier; however, when loperamide-containing nanoparticles are coated with polysorbate 80 and injected, the results were the same as typical opiates and opioids -- long, effective analgesia.