Nephrotoxicity - Wikipedia
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are …
Nephrotoxicity: Role and significance of renal biomarkers in …
Nephrotoxicity is defining as rapid deterioration in the kidney function due to toxic effect of medications and chemicals. There are various forms, and some drugs may affect renal function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
Nephrotoxic Medications - StatPearls - NCBI Bookshelf
2023年6月21日 · Nephrotoxic medications can elicit damage to the kidney via various mechanisms, including alteration in its structure and function. When evaluating the primary etiologies in renal injury, the incidence of drug-induced …
Drug-Induced Nephrotoxicity | AAFP
2008年9月15日 · Drugs shown to cause nephrotoxicity exert their toxic effects by one or more common pathogenic mechanisms. Drug-induced nephrotoxicity tends to be more common among certain patients and in...
In this review, we discuss the common nephrotoxic renal syndromes, the mechanisms of nephrotoxicity of specific commonly used drugs, the associated risk factors for renal injury, and strategies for preventing renal injury. Be vigilant.
Drug-Induced Nephrotoxicity and Its Biomarkers - PMC
Nephrotoxicity occurs when kidney-specific detoxification and excretion do not work properly due to the damage or destruction of kidney function by exogenous or endogenous toxicants. Exposure to drugs often results in toxicity in kidney which represents the major control system maintaining homeostasis of body and thus is especially susceptible ...
The Mechanism of Drug Nephrotoxicity and the Methods for …
Nephrotoxicity is dose-dependent in the case of drugs causing kidney injury following the mechanism of ATN or tubular obstruction by crystals or casts containing drugs and their metabolites. The duration of treatment is particularly important in the case of aminoglycosides and amphotericin [ 106 , 110 ].
Nephrotoxicity and Renal Pathophysiology: A Contemporary …
2018年6月25日 · Nephrotoxicity can be defined as the adverse effect of substances on renal function (Perazella, 2009). These substances can include molds and fungi, cancer therapeutics such as cisplatin, antibiotics such as aminoglycosides, metals such as mercury, arsenic and lead, and drugs of abuse such as cocaine.
Nephrotoxicity - an overview | ScienceDirect Topics
Nephrotoxicity occurs when the kidneys fail to function efficiently, resulting from damage to the kidneys by either any exogenous or endogenous toxins. Exposure to certain drugs in the kidney often leads to toxicity.
Toxic Nephropathies: Core Curriculum 2010 - American Journal …
2009年12月31日 · Toxic nephropathies are an important and relatively common category of kidney damage. Although they generally are reversible when detected early, they may be permanent, leading to chronic kidney disease (CKD).
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