Neuroprotection - Wikipedia
Lithium exerts neuroprotective effects and stimulates neurogenesis via multiple signaling pathways; it inhibits glycogen synthase kinase-3 (GSK-3), upregulates neurotrophins and growth factors (e.g., brain-derived neurotrophic factor (BDNF)), modulates inflammatory molecules, upregulates neuroprotective factors (e.g., B-cell lymphoma-2 (Bcl-2 ...
Neuroprotection - an overview | ScienceDirect Topics
This chapter presents an overview on neuroprotective natural products, predominantly from plant origins, their plausible mechanisms of actions, and in silico approaches to identify natural products leads with potential neuroprotective and therapeutic applications in CNS disorders.
Neuroprotection - an overview | ScienceDirect Topics
The neuroprotective and inhibitory actions of anti-angiogenic, anti-inflammatory agents and free radical scavengers against neurodegeneration process are well understood [271,272]. In the pathogenesis of neurodegenerative conditions, neuroinflammation may drive the progression of the disease to a chronic condition as the result of production of ...
Mechanisms and Potential Benefits of Neuroprotective Agents in ...
2024年12月18日 · Neuroprotective agents prevent apoptosis by modulating molecules that play a role in apoptosis. In addition, they can improve impaired brain functions by supporting neuroplasticity and neurogenesis. Due to the important roles that these agents play in central nervous system damage or neurodegenerative diseases, it is important to elucidate many ...
Neuroprotective Agent - an overview | ScienceDirect Topics
Neuroprotective agents refer to medications that have the potential to reduce damage caused by stroke by altering metabolic events after the onset of ischemia. These agents, including calcium channel blockers, naloxone, gangliosides, glutamate antagonists, and free-radical scavengers, have shown promise in theory and laboratory settings but ...
Neuroprotection in Acute Ischemic Stroke: A Battle Against the …
Neuroprotective agents are important to investigate as they may reduce mortality, lessen disability, and improve quality of life after AIS. In our review, we will discuss the main types of management and the different modalities of neuroprotection, their mechanisms of action, and evidence of their effectiveness after ischemic stroke.
Neuroprotection in acute brain injury: an up-to-date review
2015年12月1日 · In this paper, we summarize the current status in terms of neuroprotective strategies, both in the immediate and later stages of acute brain injury in adults. We also review potential new strategies and highlight areas for future research.
Neuroprotection strategies in traumatic brain injury: Studying the ...
It is crucial to comprehend how different neuroprotective methods and treatments can be effective in reducing the impact of TBI and enhancing patient outcomes. This review intends to cover a broad spectrum of neuroprotective approaches, encompassing pharmaceutical treatments, natural compounds, as well as cellular and molecular methods.
Neuroprotection in Neurodegenerative Disease: From Basic …
Besides its regulatory effects in the light-dark cycle, melatonin is a hormone with neuroprotective, anti-inflammatory, and antioxidant properties. J. M. Mack and colleagues reviewed the literature about the potential role of the melatoninergic system in the pathogenesis and treatment of PD.
Neuroprotection: Method and Protocols | SpringerLink
This volume contains cutting-edge molecular biology methods on neuroprotective mechanisms and specific preclinical models of the CNS injury, iseases and planning translation.